LIMA1 抗体 (AA 230-280)
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北京 101111
Quick Overview for LIMA1 抗体 (AA 230-280) (ABIN5690040)
抗原
See all LIMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280
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特异性
- LIMA1 antibody is human specific. At least four isoforms of LIMA1 are known to exist, this antibody will only detect the three largest isoforms.
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纯化方法
- LIMA1 antibody is affinity chromatography purified via peptide column.
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免疫原
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LIMA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human LIMA1.
The immunogen is located within amino acids 230 - 280 of LIMA1. -
亚型
- IgG
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anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 1-598) antibody
LIMA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (N-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 斑马鱼, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 143-192) antibodyLIMA1 适用: 人, 小鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 502-551) antibodyLIMA1 适用: 人, 小鼠, 兔, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (Middle Region) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- LIMA1 antibody can be used for detection of LIMA1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LIMA1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- LIMA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
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别名
- LIMA1
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背景
- The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines (1,2). LIMA1 is also a key molecule linking the cadherin-catenin complex to the actin cytoskeleton (3). Recent studies have shown that EGF activates ERK1/2-dependent phosphorylation, ubiquitination and degradation of LIMA1, leading to increased invasiveness and metastasis of metastatic prostate cancer models (4).
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分子量
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Predicted: 50, 66, 84 kDa
Observed: 65 kDa -
基因ID
- 51474
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NCBI登录号
- NP_001107018
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UniProt
- Q9UHB6
抗原
-
