KREMEN2 抗体 (AA 390-440)
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- 抗原 See all KREMEN2 抗体
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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抗原表位
- AA 390-440
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KREMEN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 特异性
- Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
- 纯化方法
- KREMEN2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
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KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 .
The immunogen is located within amino acids 390 - 440 of KREMEN2. - 亚型
- IgG
- Top Product
- Discover our top product KREMEN2 Primary Antibody
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anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 121-220) antibody
KREMEN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 1-420) antibodyKREMEN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 200-360) antibodyKREMEN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- KREMEN2 Antibody can be used for detection of KREMEN2 by Western blot starting at 1 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- KREMEN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- KREMEN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- 别名
- KREMEN2 (KREMEN2 产品)
- 别名
- krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody
- 背景
- KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders.
- 分子量
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Predicted: 51 kDa
Observed: 54 kDa - 基因ID
- 79412
- NCBI登录号
- NP_757384
- UniProt
- Q8NCW0
- 途径
- WNT signaling
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