KDM1B 抗体 (AA 80-130)
Our Local Distributor
北京 101111
Quick Overview for KDM1B 抗体 (AA 80-130) (ABIN5690029)
抗原
See all KDM1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 80-130
-
特异性
- KDM1B antibody is human, mouse and rat reactive. At least two isoforms of KDM1B are known to exist, this KDM1B antibody will detect both isoforms.
-
纯化方法
- KDM1B antibody is affinity chromatography purified via peptide column.
-
免疫原
-
KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B.
The immunogen is located within amino acids 80 - 130 of KDM1B. -
亚型
- IgG
-
-
-
-
应用备注
- KDM1B antibody can be used for detection of KDM1B by Western blot at 0.5 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- KDM1B antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- KDM1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
-
别名
- KDM1B
-
背景
- Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints, targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).
-
分子量
-
Predicted: 90 kDa
Observed: 90 kDa -
基因ID
- 221656
-
NCBI登录号
- NP_694587
-
UniProt
- Q8NB78
-
途径
- Warburg Effect
抗原
-