DIS3L2 抗体 (AA 720-770)
Quick Overview for DIS3L2 抗体 (AA 720-770) (ABIN5689946)
抗原
See all DIS3L2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-770
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特异性
- DIS3L2 antibody is human, mouse and rat reactive. At least three isoforms of DIS3L2 are known to exist, this antibody will only detect the longest isoform. DIS3L2 is predicted to not cross-react with DIS3 or DIS3L.
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纯化方法
- DIS3L2 antibody is affinity chromatography purified via peptide column.
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免疫原
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DIS3L2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DIS3L2.
The immunogen is located within amino acids 720 - 770 of DIS3L2. -
亚型
- IgG
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anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 27-250) antibody
DIS3L2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C7B2 unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 201-400) antibodyDIS3L2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 121-170) antibodyDIS3L2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 适用: Drosophila melanogaster WB 宿主: 山羊 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 1-619) antibodyDIS3L2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- DIS3L2 antibody can be used for detection of DIS3L2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DIS3L2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- DIS3L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
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别名
- DIS3L2
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背景
- The exosome is involved in a multitude of cellular RNA processing and degradation events (1). DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species (2). DIS3L2 is a paralog of DIS3, but unlike DIS3 is located in the cytoplasm (3). DIS3L2 defines a novel eukaryotic RNA degradation pathway and preferentially targets uridylated RNA (4). DIS3L2 mutations have also been associated with sporadic Wilms tumors (3).
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分子量
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Predicted: 97 kDa
Observed: 94 kDa -
基因ID
- 129563
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NCBI登录号
- NP_689596
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UniProt
- Q8IYB7
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途径
- Stem Cell Maintenance
抗原
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