Glutamate Receptor 1 抗体 (pSer836)
Quick Overview for Glutamate Receptor 1 抗体 (pSer836) (ABIN5689695)
抗原
See all Glutamate Receptor 1 (GLUR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer836
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特异性
- This antibody detects endogenous level of GluR1 only when phosphorylated at serine 836.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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免疫原
- GluR1 (phospho-Ser836) antibody was raised against a peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- Glutamate Receptor 1 (GLUR1)
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别名
- GluR1
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背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 110 kDa
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基因ID
- 2890
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NCBI登录号
- NP_000818
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UniProt
- P42261
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途径
- PI3K-Akt Signaling
抗原
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