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Caspase 3 抗体 (AA 29-33)

This anti-Caspase 3 antibody is a 兔 多克隆 antibody detecting Caspase 3 in WB. Suitable for 人.
产品编号 ABIN5689549
发货至: 中国

Quick Overview for Caspase 3 抗体 (AA 29-33) (ABIN5689549)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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宿主

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克隆类型

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多克隆

标记

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This Caspase 3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 29-33

    特异性

    This antibody detects endogenous level of total Caspase 3 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    Caspase 3 antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
  • 应用备注

    Western Blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase 3

    背景

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

    分子量

    35 19 17 kDa

    基因ID

    836

    NCBI登录号

    NP_004337

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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