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FLT3 抗体 (AA 589-593)

Name: FLT3 抗体 (AA 589-593)
SKU: ABIN5689528
Availability: OutOfStock

This anti-FLT3 antibody is a 兔多克隆 antibody detecting FLT3 in WB 和 IF. Suitable for 人.

产品编号 ABIN5689528

发货至: 中国

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Quick Overview for FLT3 抗体 (AA 589-593) (ABIN5689528)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This FLT3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

Discover our top product FLT3 Primary Antibody

抗原表位
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9

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2

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2

2

1

1

1

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1
AA 589-593

特异性

This antibody detects endogenous level of total FLT3 protein.

纯化方法

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

免疫原

FLT3 (Ab-591) antibody was raised against a peptide sequence around aa.589~593 (Y-F-Y-V-D) derived from Human FLT3.
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

应用备注

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store antibody at -20°C for up to one year.
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

FLT3

背景

FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

分子量

130, 160 kDa

基因ID

2322

NCBI登录号

NP_004110

UniProt

P36888

途径

RTK signaling