BIM 抗体 (AA 67-71)
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Quick Overview for BIM 抗体 (AA 67-71) (ABIN5689506)
抗原
See all BIM (BCL2L11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 67-71
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特异性
- This antibody detects endogenous level of total BIM protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- BIM (Ab-69) antibody was raised against a peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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别名
- BIM
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背景
- Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
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分子量
- 23 kDa
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基因ID
- 10018
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NCBI登录号
- NP_006529
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UniProt
- O43521
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途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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