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Nanog 抗体 (AA 137-141)

This 兔 多克隆 anti-Nanog antibody specifically detects Nanog in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN5689402
发货至: 中国
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Room 801-803
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Quick Overview for Nanog 抗体 (AA 137-141) (ABIN5689402)

抗原

See all Nanog (NANOG) 抗体
Nanog (NANOG) (Nanog Homeobox (NANOG))

适用

  • 146
  • 58
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  • 1
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人, 小鼠

宿主

  • 137
  • 16
  • 3
  • 1

克隆类型

  • 119
  • 38
多克隆

标记

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This Nanog antibody is un-conjugated

应用范围

  • 119
  • 61
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  • 26
  • 16
  • 15
  • 9
  • 8
  • 5
  • 1
  • 1
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  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 16
    • 9
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    • 1
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    • 1
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    AA 137-141

    特异性

    This antibody detects endogenous level of total Nanog protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    Nanog antibody was raised against a peptide sequence around aa.137~141 (K-Q-V-K-T) derived from Nano g.
  • 应用备注

    Western Blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    Nanog

    背景

    Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation

    分子量

    42 kDa

    基因ID

    79923

    NCBI登录号

    NP_079141

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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