KIT Ligand 抗体 (AA 265-269)
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Quick Overview for KIT Ligand 抗体 (AA 265-269) (ABIN5689307)
抗原
See all KIT Ligand (KITLG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 265-269
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特异性
- This antibody detects endogenous level of total SCF protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- SCF antibody was raised against a peptide sequence around aa.265~269 (E-K-E-R-E) derived from Human SCF.
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anti-KIT Ligand (KITLG) (AA 151-250) antibody
KITLG 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, IHC, ELISA, IHC (p), Neut 宿主: 山羊 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 26-190) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 244-273) antibodyKITLG 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 180-229) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 26-214) antibodyKITLG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 201-234), (C-Term) antibodyKITLG 适用: 人 WB 宿主: 兔 Polyclonal RB50736 unconjugated
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- KIT Ligand (KITLG)
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别名
- SCF
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背景
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1, 4, 5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.
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分子量
- 25 - 38 kDa
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基因ID
- 4254
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NCBI登录号
- NP_000890
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UniProt
- P21583
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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