电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

HDAC5 抗体 (AA 496-500)

This anti-HDAC5 antibody is a 兔 多克隆 antibody detecting HDAC5 in WB 和 IHC. Suitable for 人.
产品编号 ABIN5689288
发货至: 中国

Quick Overview for HDAC5 抗体 (AA 496-500) (ABIN5689288)

抗原

See all HDAC5 抗体
HDAC5 (Histone Deacetylase 5 (HDAC5))

适用

  • 86
  • 62
  • 43
  • 33
  • 28
  • 18
  • 12
  • 2
  • 2
  • 2
  • 1

宿主

  • 83
  • 3

克隆类型

  • 83
  • 3
多克隆

标记

  • 52
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HDAC5 antibody is un-conjugated

应用范围

  • 73
  • 33
  • 30
  • 24
  • 22
  • 15
  • 9
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 25
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 496-500

    特异性

    This antibody detects endogenous level of total HDAC5 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    HDAC5 (Ab-498) antibody was raised against a peptide sequence around aa.496~500 (T-Q-S-S-P) derived from Human HDAC5/7.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    HDAC5 (Histone Deacetylase 5 (HDAC5))

    别名

    HDAC5

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    124 kDa

    基因ID

    10014

    NCBI登录号

    NP_001015053

    UniProt

    Q9UQL6

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
You are here:
Chat with us!