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SAPK, JNK (AA 181-185) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in IHC 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689246
发货至: 中国

Quick Overview for SAPK, JNK (AA 181-185) 抗体 (ABIN5689246)

抗原

SAPK, JNK

适用

人, 小鼠, 大鼠

宿主

  • 15
  • 1

克隆类型

  • 15
  • 1
多克隆

标记

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 9
  • 7
  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 181-185

    特异性

    This antibody detects endogenous level of total SAPK/JNK protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    SAPK, JNK

    别名

    SAPK / JNK

    背景

    Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

    分子量

    46, 54 kDa

    基因ID

    5601

    NCBI登录号

    NP_001128516

    UniProt

    P45984, P53779
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