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SAPK, JNK (AA 181-185) 抗体

适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362918
发货至: 中国
  • 抗原
    SAPK, JNK
    抗原表位
    • 15
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 181-185
    适用
    • 15
    • 12
    • 12
    • 7
    人, 小鼠, 大鼠
    宿主
    • 21
    • 1
    克隆类型
    • 21
    • 1
    多克隆
    标记
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    非结合性
    应用范围
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    特异性
    The antibody detects endogenous level of total SAPK/JNK protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Peptide sequence around AA 181-185 (M-M-T-P-Y) derived from Human SAPK, JNK. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Thévenin, Zony, Bahnson, Colman: "Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts." in: Protein expression and purification, Vol. 75, Issue 2, pp. 138-46, (2010) (PubMed).

  • 抗原
    SAPK, JNK
    别名
    SAPK/JNK
    别名
    JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, SAPK1a antibody, p54a antibody, p54aSAPK antibody, AI851083 antibody, Prkm9 antibody, mitogen-activated protein kinase 9 antibody, MAPK9 antibody, Mapk9 antibody
    背景
    Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
    分子量
    54 kDa
    NCBI登录号
    NP_001128
    UniProt
    P53779
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