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PLK1 抗体 (pThr210)

The 兔 多克隆 anti-PLK1 antibody is suitable to detect PLK1 in samples from 人, 小鼠, 大鼠, 非洲爪蟾, Cow, 犬 和 斑马鱼. It has been validated for WB.
产品编号 ABIN5688913
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLK1 抗体 (pThr210) (ABIN5688913)

抗原

See all PLK1 抗体
PLK1 (Polo-Like Kinase 1 (PLK1))

适用

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人, 小鼠, 大鼠, 非洲爪蟾, Cow, 犬, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This PLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pThr210

    纯化方法

    Affinity Purified

    免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr210 of PLK1.
  • 应用备注

    The antibody has been directly tested for reactivity in Western blots in rat and human tissues. It is anticipated that the antibody will react with bovine, canine, mouse, non-human primate, Xenopus and Zebrafish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    PLK1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    PLK1 (Polo-Like Kinase 1 (PLK1))

    别名

    PLK1

    背景

    Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK's is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).

    分子量

    66 kDa

    基因ID

    5347

    UniProt

    P53350

    途径

    Cell Division Cycle, M Phase
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