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14-3-3 theta 抗体 (pSer58)

This anti-14-3-3 theta antibody is a 兔 多克隆 antibody detecting 14-3-3 theta in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 非洲爪蟾, 斑马鱼 和 绵羊.
产品编号 ABIN5688906
发货至: 中国

Quick Overview for 14-3-3 theta 抗体 (pSer58) (ABIN5688906)

抗原

See all 14-3-3 theta (YWHAQ) 抗体
14-3-3 theta (YWHAQ)

适用

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人, 小鼠, 大鼠, Cow, 小鸡, 犬, 非洲爪蟾, 斑马鱼, 绵羊

宿主

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克隆类型

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多克隆

标记

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This 14-3-3 theta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer58

    纯化方法

    Affinity Purified

    免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser58 of rat 14-3-3 protein.
  • 应用备注

    The antibody has been directly tested for reactivity in Western blots with human and rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, mouse, non-human primates, sheep, Xenopus and zebra fish based on the fact that these species have 100 % homology with the amino acid sequence used as antigen for this antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    14-3-3 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    14-3-3 theta (YWHAQ)

    别名

    14-3-3

    背景

    14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004, Dougherty and Morrison, 2004). The14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking. These functions of 14-3-3 proteins are facilitated by, if not dependent on, its dimeric structure. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation (Woodcock et al., 2003).

    分子量

    29 kDa

    基因ID

    56011

    UniProt

    P35213

    途径

    Apoptosis, Myometrial Relaxation and Contraction
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