Potassium Channel (pSer503) 抗体
The 兔 多克隆 anti-Potassium Channel antibody (ABIN5688902) specifically detects Potassium Channel in WB 和 IHC.
The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN5688902
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Potassium Channel (pSer503) 抗体 (ABIN5688902)
抗原
Potassium Channel
适用
大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
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抗原表位
- pSer503
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纯化方法
- Affinity Purified
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH).
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应用备注
- The antibody has been directly tested for reactivity in Western blots with rat and mouse tissue.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Potassium Channel antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Potassium Channel
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背景
- Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995, Pongs, 1999, Blaine and Ribera, 1998, Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).
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分子量
- 100 kDa
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基因ID
- 25327
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UniProt
- P25122
抗原
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