Potassium Channel 抗体
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北京 101111
Quick Overview for Potassium Channel 抗体 (ABIN306719)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Rat Potassium Channel
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交叉反应
- 大鼠
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产品特性
- Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to Icurrent in heart and current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits In response to membrane depolarization, Kv4.2 channels accumulate in the closed-inactivated state(s), from which they directly recover, bypassing the open state. Kv4.2 is a substrate for ERK in vitro and in vivo, and suggest that ERK may regulate potassium-channel function by direct phosphorylation of the pore-forming alpha subunit.
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纯化方法
- Ammonium Sulfate Precipitation
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亚型
- IgG
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应用备注
- Optimal antibody concentration should be evaluated by serial dilutions. Suggested Western Blot dilution 1:1000. Other applications: Immunoprecipitation, immunofluorescence.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Potassium Channel
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背景
- RK5, Shal1, Kcnd2, Potassium voltage-gated channel subfamily D member 2
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UniProt
- Q63881
抗原
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