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Parkin 抗体 (pSer101)

PARK2 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5688885
发货至: 中国
  • 抗原 See all Parkin (PARK2) 抗体
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    抗原表位
    • 16
    • 16
    • 16
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer101
    适用
    • 74
    • 28
    • 27
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    人, Cow
    宿主
    • 98
    • 7
    • 1
    克隆类型
    • 100
    • 6
    多克隆
    标记
    • 51
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Parkin antibody is un-conjugated
    应用范围
    • 94
    • 39
    • 39
    • 37
    • 21
    • 20
    • 16
    • 16
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity Purified
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser101 of human parkin.
    Top Product
    Discover our top product PARK2 Primary Antibody
  • 应用备注
    The antibody has been directly tested for reactivity in Western blots with human tissue. It is anticipated that the antibody will react with bovine and non-human primate tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
    储存条件
    -20 °C
    储存方法
    Parkin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    别名
    Parkin (PARK2 产品)
    别名
    CG10523 antibody, Dmel\\CG10523 antibody, Dpark antibody, SD01679 antibody, dpk antibody, AR-JP antibody, LPRS2 antibody, PDJ antibody, PRKN antibody, Park antibody, Prkn antibody, si:ch211-123f21.1 antibody, zgc:112390 antibody, pdr-1 antibody, PARK2 antibody, parkin antibody, parkin RBR E3 ubiquitin protein ligase antibody, Parkinson disease (autosomal recessive, juvenile) 2, parkin antibody, park antibody, PRKN antibody, Prkn antibody, prkn antibody, CpipJ_CPIJ014867 antibody, Park2 antibody
    背景
    Parkin is an E3 ligase in the ubiquitin-proteasome system. Hereditary Parkinson's disease is most commonly caused by mutations in the parkin gene and is characterized by the progressive loss of dopaminergic neurons and the presence of Lewy bodies in the substania nigra (Jenner aet al.,1992). Recent evidence suggests that phosphorylation of parkin at Ser101 may have an important regulatory role on its E3 ubiquitin ligase activity (Yamamoto et al., 2005).
    分子量
    52 kDa
    基因ID
    5071
    UniProt
    O60260
    途径
    Autophagy, Ubiquitin Proteasome Pathway
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