BMP4 抗体
Quick Overview for BMP4 抗体 (ABIN5688733)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- This IgG2bK antibody was purified from cell culture by Protein G affinity chromatography.
-
免疫原
- BMP-4 antibody is produced in mice using highly pure (>98%) recombinant human BMP-4 as the immunizing antigen.
-
-
anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibody
BMP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C11C7 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3C11H8 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibodyBMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibody (APC)BMP4 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
-
Neutralization:
To yield one-half maximal inhibition [ND50] of the biological activity of hBMP-4 (5.0 ng/mL), a concentration of 0.4-0.6 μ,g/mL of this antibody is required.
ELISA:
In a sandwich ELISA (assuming 100 μ,L/well), a concentration of 4.0-8.0 μ,g/mL of this antibody will detect at least 2000 pg/mL of recombinant human BMP-4 when used in conjunction with compatible secondary reagents.
Western Blot:
To detect hBMP-4 by Western Blot analysis this antibody can be used at a concentration of 0.25-0.50 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBMP-4 is 2.0-4.0 ng/lane, under non-reducing conditions. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
储存条件
- 4 °C,-20 °C
-
储存方法
- BMP-4 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4°C when reconstituted.
-
-
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
-
别名
- BMP-4
-
背景
- BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
-
基因ID
- 652
-
UniProt
- P12644
-
途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
-
