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PD-1 抗体 (AA 25-167)

This anti-PD-1 antibody is a Llama 单克隆 antibody detecting PD-1 in FACS 和 ELISA. Suitable for 人.
产品编号 ABIN5688354
发货至: 中国

Quick Overview for PD-1 抗体 (AA 25-167) (ABIN5688354)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

片段

single-domain Antibody (sdAb)

适用

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宿主

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Llama

克隆类型

  • 173
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  • 5
单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA

克隆位点

F1-2A8
  • 抗原表位

    • 16
    • 11
    • 5
    • 5
    • 5
    • 5
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    AA 25-167

    纯化方法

    PD-1 Antibody is affinity chromatography purified via Nickel column.

    免疫原

    PD-1 antibody was raised against a recombinant protein corresponding to amino acids 25 - 167 of human PD-1.
  • 应用备注

    PD-1 antibody can be used for detection of PD-1 by ELISA and FACS (10 μ,g/mL).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PD-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    PD-1 antibody should be stored in working aliquots at -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    PD-1

    背景

    PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

    基因ID

    5133

    NCBI登录号

    NP_005009

    UniProt

    Q15116

    途径

    Cancer Immune Checkpoints
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