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Peripherin 抗体

This 小鸡 多克隆 antibody specifically detects Peripherin in WB 和 IHC. It exhibits reactivity toward 哺乳动物.
产品编号 ABIN5687475
发货至: 中国
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Quick Overview for Peripherin 抗体 (ABIN5687475)

抗原

See all Peripherin (PRPH) 抗体
Peripherin (PRPH)

适用

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哺乳动物

宿主

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小鸡

克隆类型

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多克隆

标记

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This Peripherin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 特异性

    Specific for the ~57  kDa peripherin protein.

    纯化方法

    Total IgY fraction

    免疫原

    Recombinant rat peripherin expressed in and purified from E. coli.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C

    储存方法

    Peripherin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    Peripherin (PRPH)

    别名

    Peripherin

    背景

    Peripherin is a ~57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.

    分子量

    57 kDa

    基因ID

    24688

    UniProt

    P21807
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