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FLT4 抗体 (Extracellular Domain)

FLT4 适用: 人 WB, IHC (p), IHC (fro), EIA 宿主: 小鼠 Monoclonal 2-00E-011 unconjugated
产品编号 ABIN567981
发货至: 中国
  • 抗原 See all FLT4 抗体
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    抗原表位
    • 16
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 74
    • 47
    • 16
    • 12
    宿主
    • 67
    • 22
    • 4
    • 2
    小鼠
    克隆类型
    • 68
    • 27
    单克隆
    标记
    • 53
    • 8
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLT4 antibody is un-conjugated
    应用范围
    • 53
    • 40
    • 35
    • 26
    • 14
    • 13
    • 13
    • 8
    • 8
    • 7
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Human VEGFR-3/FLT-4. Other species not tested.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Recombinant Human Vascular Endothelial Growth Factor Receptor 3 (rh VEGFR-3/FLT-4) extracellular domain
    克隆位点
    2-00E-011
    亚型
    IgG1
    Top Product
    Discover our top product FLT4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore in Sterile water to a concentration of 0.1-1.0 mg/mL
    浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.4 without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C for 6 month or at -20 °C for longer. Following reconstitution store the antibody undiluted at 2-8 °C for one month.
    有效期
    6 months
  • 抗原
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    别名
    VEGFR-3 / Flt-4 (FLT4 产品)
    别名
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    背景
    VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk 1) and VEGFR-3 (FLT-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular and lymphatic endothelial cells and to the monocyte/macrophage lineage. These receptors play essential roles in vasculogenesis, hematopoiesis, angiogenesis and lymphangiogenesis. The VEGFR-3 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGFR-3 is composed of a 751 aa residue extracellular domain, a 22 aa residue transmembrane domain and a 482 aa residue cytoplasmic domain. Both VEGF-C and VEGF-D have been shown to bind and activate VEGF R3 (Flt-4). The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stage of development. It is important for lymphangiogenesis.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3
    基因ID
    2324
    NCBI登录号
    NP_002011
    UniProt
    P35916
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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