FLT4 抗体
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Quick Overview for FLT4 抗体 (ABIN567980)
抗原
See all FLT4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody will detect VEGFR-3/FLT-4 in WB in PAEC/FLT-4 cells.
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纯化方法
- Protein G Chromatography
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免疫原
- Purified, insect cell-derived recombinant Mouse soluble FLT-4 (120 kDa).
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS pH 7.4 without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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别名
- VEGFR-3 / Flt-4
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背景
- Mature native mouse VEGF Receptor 3 (Flt4) is composed of a 751 amino acid residue extracellular domain, a 22 amino acid residue transmembrane domain, and a 565 amino acid residue cytoplasmic domain. Recombinant mature mouse VEGF Receptor 3/Fc is a disulfidelinked dimeric protein. Based on N-terminal sequencing, recombinant mouse VEGF Receptor 3/Fc has Met 17 at the amino-terminus. The amino acid sequence of mouse VEGF Receptor 3 is 88 % identical to human VEGF Receptor 3. VEGF Receptor 3 is a specific marker for lymphatic vessels. In adults, VEGF Receptor 3 expression is restricted to endothelial cells of the lymphatic vessels. It has also been detected on some high endothelial venules, in embryonic prelymphatic blood vessels, in some tumor blood vessels, and in certain hematopoietic and leukemia cells. The predominant role of VEGF Receptor 3 is its involvement in the development of the lymphatic vessel system. Both VEGFC and VEGFD bind and activate the receptors, VEGF Receptor 3 and VEGF Receptor 2.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3
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基因ID
- 14257
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NCBI登录号
- NP_032055
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UniProt
- P35917
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
抗原
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