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FLT4 抗体

This anti-FLT4 antibody is a 大鼠 单克隆 antibody detecting FLT4 in WB. Suitable for 小鼠.
产品编号 ABIN567980
发货至: 中国

Quick Overview for FLT4 抗体 (ABIN567980)

抗原

See all FLT4 抗体
FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

适用

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小鼠

宿主

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大鼠

克隆类型

  • 79
  • 35
单克隆

标记

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This FLT4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

7A3
  • 特异性

    This antibody will detect VEGFR-3/FLT-4 in WB in PAEC/FLT-4 cells.

    纯化方法

    Protein G Chromatography

    免疫原

    Purified, insect cell-derived recombinant Mouse soluble FLT-4 (120 kDa).

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS pH 7.4 without preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

    别名

    VEGFR-3 / Flt-4

    背景

    Mature native mouse VEGF Receptor 3 (Flt4) is composed of a 751 amino acid residue extracellular domain, a 22 amino acid residue transmembrane domain, and a 565 amino acid residue cytoplasmic domain. Recombinant mature mouse VEGF Receptor 3/Fc is a disulfidelinked dimeric protein. Based on N-terminal sequencing, recombinant mouse VEGF Receptor 3/Fc has Met 17 at the amino-terminus. The amino acid sequence of mouse VEGF Receptor 3 is 88 % identical to human VEGF Receptor 3. VEGF Receptor 3 is a specific marker for lymphatic vessels. In adults, VEGF Receptor 3 expression is restricted to endothelial cells of the lymphatic vessels. It has also been detected on some high endothelial venules, in embryonic prelymphatic blood vessels, in some tumor blood vessels, and in certain hematopoietic and leukemia cells. The predominant role of VEGF Receptor 3 is its involvement in the development of the lymphatic vessel system. Both VEGFC and VEGFD bind and activate the receptors, VEGF Receptor 3 and VEGF Receptor 2.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3

    基因ID

    14257

    NCBI登录号

    NP_032055

    UniProt

    P35917

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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