RAD21 抗体 (C-Term)
Quick Overview for RAD21 抗体 (C-Term) (ABIN567792)
抗原
See all RAD21 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 544-631, C-Term
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特异性
- This antibody reacts with Cohesin (120 kDa) on Western blotting.
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纯化方法
- Protein-A Agarose Chromatography of hybridoma supernatant.
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免疫原
- Recombinant C-terminal fragment (544-631 aa) of Scc1 subunit of Human Cohesin (hRad21).
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- RAD21 (RAD21 Homolog (RAD21))
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别名
- RAD21
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背景
- Cohesin in eukaryotic cells is mediated by a multisubunit protein complex. Cohesin consists of four proteins: Smc1, Smc3, Scc1/Mcd1/hRad21, which is called kleisin and is the target of the protease separase, and Scc3/Irr1. Cohesin holds sister chromatids together until they separate into daughter cells during mitosis and also prevents splitting of chromosomes once bipolar attachments are made.Synonyms: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog
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基因ID
- 5885
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NCBI登录号
- NP_006256
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UniProt
- O60216
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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