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ATF3 抗体

This anti-ATF3 antibody is a 小鼠 单克隆 antibody detecting ATF3 in ICC 和 DB. Suitable for 人.
产品编号 ABIN5676162
发货至: 中国

Quick Overview for ATF3 抗体 (ABIN5676162)

抗原

See all ATF3 抗体
ATF3 (Activating Transcription Factor 3 (ATF3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ATF3 antibody is un-conjugated

应用范围

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Immunocytochemistry (ICC), Dot Blot (DB)

克隆位点

44C3a
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    ATF3 antibody was raised in mouse using recombinant Human Activating Transcription Factor 3

    亚型

    IgG1
  • 应用备注

    ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    ATF3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    ATF3 (Activating Transcription Factor 3 (ATF3))

    别名

    ATF3

    背景

    Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive elementbinding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. Synonyms: Monoclonal ATF3 antibody, Anti-ATF3 antibody, Cyclic AMP-dependent transcription factor ATF-3 antibody.

    途径

    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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