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BUB1B 抗体

BUB1B 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal 8G1 unconjugated
产品编号 ABIN567606
发货至: 中国
  • 抗原 See all BUB1B 抗体
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    适用
    • 71
    • 35
    • 14
    • 3
    • 1
    宿主
    • 54
    • 17
    • 4
    小鼠
    克隆类型
    • 54
    • 21
    单克隆
    标记
    • 46
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BUB1B antibody is un-conjugated
    应用范围
    • 61
    • 25
    • 24
    • 22
    • 14
    • 12
    • 12
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with BUBR1 (121 kDa) on Western blotting, Immunoprecipitation and Immunocytochemistry.
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    克隆位点
    8G1
    亚型
    IgG1
    Top Product
    Discover our top product BUB1B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    储存液
    Without preservative
  • 抗原
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    别名
    BUB1B (BUB1B 产品)
    背景
    Metaphase checkpoint controls sense abnormalities in chromosome alignment during mitosis and prevent progression to anaphase until proper alignment has been attained. A number of proteins, including Mitotic arrest deficiency protein 2 (MAD2), Budding uninhibited benzimidazole 1 (BUB1) and Budding uninhibited benzimidazole receptor 1 (BUBR1), have been implicated in the metaphase checkpoint control in mammalian cells. BUB1 and BUBR1 both localize to kinetochores during mitosis, suggesting that they play a role in delaying anaphase until all chromosomes achieve correct, bipolar attachment to the spindle. BUB1 and BUBR1 respond differently to spindle dynamics, they are part of a common complex during mitosis and BUB1 and BUBR1 may integrate different 'spindle assembly signals' into a single signal which can then be interpreted by downstream cell cycle regulators.Synonyms: BUB1 beta, BUBR1, MAD3/BUB1-related protein kinase, MAD3L, Mitotic checkpoint kinase MAD3L, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein SSK1
    基因ID
    701
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