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RAD51D 抗体 (AA 1-100) (Biotin)

This anti-RAD51D antibody is a 兔 多克隆 antibody detecting RAD51D in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN5675750
发货至: 中国

Quick Overview for RAD51D 抗体 (AA 1-100) (Biotin) (ABIN5675750)

抗原

See all RAD51D 抗体
RAD51D (RAD51 Homolog D (RAD51D))

适用

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宿主

  • 26
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克隆类型

  • 25
  • 5
多克隆

标记

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This RAD51D antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 4
    • 4
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 1-100

    交叉反应

    预测反应

    Mouse,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RAD51D

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    RAD51D (RAD51 Homolog D (RAD51D))

    别名

    RAD51D

    背景

    Synonyms: DNA repair protein RAD51 homolog 4, RAD51D, R51H3, RAD51 homolog D RAD51-like protein 3, TRAD, RAD51D, RAD51L3

    Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

    基因ID

    5892

    UniProt

    O75771
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