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RAD51D 抗体 (C-Term)

RAD51D 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259591
发货至: 中国
  • 抗原 See all RAD51D 抗体
    RAD51D (RAD51 Homolog D (RAD51D))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 28
    • 3
    • 3
    • 1
    • 1
    宿主
    • 22
    • 5
    • 1
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAD51D antibody is un-conjugated
    应用范围
    • 19
    • 10
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RAD51L3 Antibody detects endogenous levels of total RAD51L3.
    预测反应
    Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RAD51L3, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RAD51D Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RAD51D (RAD51 Homolog D (RAD51D))
    别名
    RAD51D (RAD51D 产品)
    别名
    R51H3 antibody, Rad51l3 antibody, TRAD antibody, RAD51 paralog D antibody, Rad51d antibody
    背景

    Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

    Gene: RAD51D

    分子量
    40 kDa
    基因ID
    5892
    UniProt
    O75771
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