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HTR2A 抗体 (AA 171-270) (HRP)

This anti-HTR2A antibody is a 兔 多克隆 antibody detecting HTR2A in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN5675441
发货至: 中国

Quick Overview for HTR2A 抗体 (AA 171-270) (HRP) (ABIN5675441)

抗原

See all HTR2A 抗体
HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

适用

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小鼠, 大鼠

宿主

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克隆类型

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  • 1
多克隆

标记

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This HTR2A antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 171-270

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human 5HT2A Receptor

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

    别名

    5HT2A Receptor

    背景

    Synonyms: 5-hydroxytryptamine receptor 2A, HTR2A, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A, HTR2A, HTR2

    Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

    基因ID

    8549

    UniProt

    P28223

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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