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PPARA 抗体 (AA 181-280)

Name: PPARA 抗体 (AA 181-280)
SKU: ABIN5675335
Availability: OutOfStock

This anti-PPARA antibody is a 兔多克隆 antibody detecting PPARA in WB, ELISA, IF (p), IF (cc), ICC, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠.

Mouse heart lysates probed with PPAR alpha Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (PPARA 抗体 (AA 181-280))

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产品编号 ABIN5675335

发货至: 中国

Datasheet as PDF

Quick Overview for PPARA 抗体 (AA 181-280) (ABIN5675335)

抗原

See all PPARA 抗体

PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PPARA antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product PPARA Primary Antibody

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AA 181-280

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Sheep,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human PPAR alpha

亚型

IgG
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 301-400) antibody
PPARA 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 61-170) antibody
PPARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibody
PPARA 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5D10C3 unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-468) antibody
PPARA 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1331CT894-186-143 unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
KO Validated PPARA 适用: 人 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibody
PPARA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5D10E10 unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (C-Term) antibody
PPARA 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 山羊, 豚鼠, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
PPARA 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF, FM 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (pSer12) antibody
PPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
PPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

别名

PPAR alpha

背景

Synonyms: hPPAR, MGC2237, MGC2452, NR1C1, Nuclear receptor subfamily 1 group C member 1, Peroxisome Proliferator Activated Receptor alpha, PPAR, PPARA, OTTHUMP00000197740, OTTHUMP00000197741, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, PPARA_HUMAN, PPARalpha. PPAR _, PPAR-_, PPAR_,
Background: Peroxisome proliferators are nongenotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed Peroxisome Proliferator Activated Receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 A6 (CYP450 A6) through interaction with specific response elements. PPAR alpha is activated by free fatty acids including linoleic, arachidonic, and oleic acids. Induction of peroxisomes by this mechanism leads to a reduction in blood triglyceride levels. PPAR alpha is expressed mainly in skeletal muscle, heart, liver, and kidney and is thought to regulate many genes involved in the beta-oxidation of fatty acids. Activation of rat liver PPAR alpha has been shown to suppress hepatocyte apoptosis. PPAR alpha, like several other nuclear hormone receptors, heterodimerizes with retinoic X receptor (RXR) alpha to form a transcriptionally competent complex.

基因ID

5465

UniProt

Q07869

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C