CHRM4 抗体 (AA 131-230) (HRP)
Quick Overview for CHRM4 抗体 (AA 131-230) (HRP) (ABIN5675328)
抗原
See all CHRM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-230
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CHRM4
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))
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别名
- CHRM4
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背景
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Synonyms: mAChR M4, Muscarinic Acetylcholine Receptor M4, Cholinergic receptor muscarinic 4, Chrm 4, CHRM4, HM 4, HM4, M4, Muscarinic acetylcholine receptor M4, ACM4_HUMAN.
Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, mouse studies link its function to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus.
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基因ID
- 1132
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UniProt
- P08173
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途径
- cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane
抗原
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