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HIPK1 抗体 (AA 1-100) (HRP)

This anti-HIPK1 antibody is a 兔 多克隆 antibody detecting HIPK1 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 猴 和 Macaque.
产品编号 ABIN5675041
发货至: 中国

Quick Overview for HIPK1 抗体 (AA 1-100) (HRP) (ABIN5675041)

抗原

See all HIPK1 抗体
HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

适用

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人, 小鼠, 猴, Macaque

宿主

  • 43
  • 5

克隆类型

  • 44
  • 4
多克隆

标记

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  • 1
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This HIPK1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    交叉反应

    人, Macaque, 猴, 小鼠

    预测反应

    Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HIPK1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

    别名

    HIPK1

    背景

    Synonyms: Hipk 1, Hipk1, HIPK1_HUMAN, Homeodomain interacting protein kinase 1, Homeodomain interacting protein kinase 1 like protein, Homeodomain-interacting protein kinase 1, Myak, Nbak 2, Nbak2, Nuclear body associated kinase 2, Nuclear body associated kinase 2b

    Background: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    基因ID

    204851

    UniProt

    Q86Z02
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