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HIPK1 抗体 (N-Term)

HIPK1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262240
发货至: 中国
  • 抗原 See all HIPK1 抗体
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 53
    • 27
    • 16
    • 15
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 48
    • 5
    克隆类型
    • 49
    • 4
    多克隆
    标记
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIPK1 antibody is un-conjugated
    应用范围
    • 40
    • 24
    • 17
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    特异性
    HIPK1 Antibody detects endogenous levels of total HIPK1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HIPK1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HIPK1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    别名
    HIPK1 (HIPK1 产品)
    别名
    HIPK1 antibody, myak antibody, nbak2 antibody, hipk1 antibody, Myak antibody, Nbak2 antibody, 1110062K04Rik antibody, homeodomain interacting protein kinase 1 antibody, homeodomain interacting protein kinase 1 L homeolog antibody, homeodomain interacting protein kinase 1 S homeolog antibody, HIPK1 antibody, hipk1.L antibody, hipk1 antibody, hipk1.S antibody, Hipk1 antibody
    背景

    Description: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    Gene: HIPK1

    分子量
    131 kDa
    基因ID
    204851
    UniProt
    Q86Z02
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