HTRA2 抗体 (AA 231-330)
Quick Overview for HTRA2 抗体 (AA 231-330) (ABIN5675033)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-330
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HTRA2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HTRA2
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背景
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Synonyms: Serine protease HTRA2, mitochondrial, HTRA2, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25 Serine proteinase OMI, HTRA2, OMI, PRSS25
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
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基因ID
- 27429
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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