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Complement Factor B 抗体 (N-Term)

CFB 适用: 人 WB, IHC, ELISA, FACS, IHC (fro), Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN5674038
发货至: 中国
  • 抗原 See all Complement Factor B (CFB) 抗体
    Complement Factor B (CFB)
    抗原表位
    • 15
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    N-Term
    适用
    • 70
    • 44
    • 35
    • 1
    • 1
    • 1
    • 1
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    宿主
    • 91
    • 14
    • 2
    小鼠
    克隆类型
    • 92
    • 14
    • 1
    单克隆
    标记
    • 45
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    • 15
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    This Complement Factor B antibody is un-conjugated
    应用范围
    • 80
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    • 29
    • 15
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    • 12
    • 10
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    特异性
    Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
    纯化方法
    Protein A purified
    免疫原
    Purified human complement factor b.
    亚型
    IgG1
    Top Product
    Discover our top product CFB Primary Antibody
  • 应用备注
    Approved: ELISA, Flo, Func, IHC, IHC-Fr, WB

    Usage: ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Borate buffered saline,  pH 8.2 - 8.4, 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    avoid freeze thaw cycles. Store undiluted.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    Complement Factor B (CFB)
    别名
    CFB / Complement Factor B (CFB 产品)
    别名
    AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody
    背景
    Name/Gene ID: CFB
    Subfamily: Serine S1
    Family: Protease

    Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
    基因ID
    629
    UniProt
    P00751
    途径
    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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