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Complement Factor B 抗体 (N-Term)

This anti-Complement Factor B antibody is a 小鼠 单克隆 antibody detecting Complement Factor B in WB, IHC, ELISA, FACS, IHC (fro) 和 Func. Suitable for 人.
产品编号 ABIN5674038
发货至: 中国

Quick Overview for Complement Factor B 抗体 (N-Term) (ABIN5674038)

抗原

See all Complement Factor B (CFB) 抗体
Complement Factor B (CFB)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Complement Factor B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
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    N-Term

    特异性

    Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.

    纯化方法

    Protein A purified

    免疫原

    Purified human complement factor b.

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, Flo, Func, IHC, IHC-Fr, WB

    Usage: ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Borate buffered saline,  pH 8.2 - 8.4, 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze thaw cycles. Store undiluted.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • 抗原

    Complement Factor B (CFB)

    别名

    CFB / Complement Factor B

    背景

    Name/Gene ID: CFB
    Subfamily: Serine S1
    Family: Protease

    Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B

    基因ID

    629

    UniProt

    P00751

    途径

    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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