MR1 抗体 (N-Term)
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北京 101111
Quick Overview for MR1 抗体 (N-Term) (ABIN5673166)
抗原
See all MR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PEFISVGYVD SHPITTYDSV TRQKEPRAPW MAENLAPDHW ERYTQLLRGW
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of Human MR1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
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别名
- MR1
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背景
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MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
Alias Symbols: HLALS
Protein Size: 32 -
分子量
- 296 kDa
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基因ID
- 3140
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NCBI登录号
- NM_001194999, NP_001181928
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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