XRN2 抗体 (C-Term)
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Quick Overview for XRN2 抗体 (C-Term) (ABIN5671406)
抗原
See all XRN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QNAAFQPNQY QMLGGPGGYP PRRDDHRGGR QGYPREGRKY PLPPPSGRYS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of Mouse XRN2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- XRN2 (5'-3' Exoribonuclease 2 (XRN2))
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别名
- XRN2
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背景
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Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites.
Protein Size: 951 -
基因ID
- 24128
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NCBI登录号
- NM_011917, NP_036047
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UniProt
- Q9DBR1
抗原
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