CERS6 抗体 (AA 62-131)
Quick Overview for CERS6 抗体 (AA 62-131) (ABIN566979)
抗原
See all CERS6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 62-131
-
原理
- Mouse monoclonal antibody raised against a partial recombinant LASS6.
-
序列
- PCAIALNIQA NGPQIAPPNA ILEKVFTAIT KHPDEKRLEG LSKQLDWDVR SIQRWFRQRR NQEKPSTLTR
-
交叉反应
- 人
-
产品特性
- Antibody Reactive Against Recombinant Protein.
-
免疫原
- LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- In 1x PBS, pH 7.4
-
注意事项
- Aliquot to avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
-
: "Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).
: "Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153009, (2016) (PubMed).
: "Bcl2L13 is a ceramide synthase inhibitor in glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 15, pp. 5682-7, (2014) (PubMed).
: "Modulation of ceramide synthase activity via dimerization." in: The Journal of biological chemistry, Vol. 287, Issue 25, pp. 21025-33, (2012) (PubMed).
: "D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ..." in: Biochimie, Vol. 93, Issue 9, pp. 1446-59, (2011) (PubMed).
: "Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells." in: Cellular signalling, Vol. 22, Issue 9, pp. 1300-7, (2010) (PubMed).
in: (PubMed).
-
: "Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).
-
- CERS6 (Ceramide Synthase 6 (CERS6))
-
别名
- LASS6
-
背景
-
Full Gene Name: LAG1 homolog, ceramide synthase 6
Synonyms: CerS6,MGC129949,MGC129950 -
基因ID
- 253782
-
NCBI登录号
- NM_203463
抗原
-