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Recombinant CD4 抗体

Name: Recombinant CD4 抗体
Brand: antibodies-online
SKU: ABIN5668250
Availability: OutOfStock

This anti-CD4 antibody is a 兔 Chimeric antibody detecting CD4 in FACS, IP, IF, IHC (p), BP 和 Inh. Suitable for 人, 猕猴和 Cynomolgus.

Flow-cytometry using anti-CD4 antibody MT310 Human lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体)

FACS

Flow-cytometry using anti-CD4 antibody MT310 Rhesus monkey lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体)

FACS

Flow-cytometry using anti-CD4 antibody MT310 Cynomolgus monkey lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体)

FACS

3 images

产品编号 ABIN5668250

发货至: 中国

Quick Overview for Recombinant CD4 抗体 (ABIN5668250)

抗原

See all CD4 抗体

CD4

抗体类型

Recombinant Antibody

适用

人, 猕猴, Cynomolgus

宿主

兔

克隆类型

Chimeric

标记

This CD4 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Peptide (BP), Inhibition (Inh)

克隆位点

MT310

Discover our top product CD4 Primary Antibody

原理

Anti-CD4 [MT310], Rabbit IgG, kappa

特异性

This antibody is specific for the CD4 extracellular domain D1 (binding the HIV-1 gp120-binding site).

交叉反应

Cynomolgus, 猕猴

产品特性

Original Species of Ab: Mouse
Original Format of Ab: IgG1

纯化方法

Protein A affinity purified

亚型

IgG kappa
anti-CD4 (CD4) (AA 385-457) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, Pig FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 犬, Pig, 兔, Cat, Cow, 绵羊, 豚鼠, 山羊, 马, Avian, 驴, Hamster WB, IHC 宿主: 山羊 Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 适用: 人 FACS, WB, MS 宿主: 小鼠 Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) (AA 301-400) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 小鼠 FACS, IP, IHC (fro), ICC, Func 宿主: 大鼠 Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 FITC

anti-CD4 (CD4) antibody (PE)
CD4 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-35 PE

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 PE

anti-CD4 (CD4) (AA 26-200) antibody
CD4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

This antibody strongly inhibits HIV-1 gp120-binding to CD4, which blocks HIV infectivity of CD4⁺ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation (possibly leading to anergy induction) (Qin et al., 2001, PMID: n/a). Additionally, antibody binding to CD4 leads to GM-CSF, TNF-α and IL-10 induction. (TNF-α induction only occurs after 20 hours.)

说明

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

限制

仅限研究用
浓度

1 mg/mL

缓冲液

PBS with 0.02 % Proclin 300.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
抗原

CD4

别名

CD4

背景

Leu3/T3, T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3

UniProt

P01730

途径

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events