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Recombinant CD4 抗体 (Extracellular Domain)

Name: Recombinant CD4 抗体 (Extracellular Domain)
Brand: antibodies-online
SKU: ABIN5668250
Availability: OutOfStock

This 兔 Chimeric antibody specifically detects CD4 in FACS, IP, IF, IHC (p), BP 和 Inh. It exhibits reactivity toward 人, 猕猴和 Cynomolgus.

Flow-cytometry using anti-CD4 antibody MT310 Human lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体 (Extracellular Domain))

FACS

Flow-cytometry using anti-CD4 antibody MT310 Rhesus monkey lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体 (Extracellular Domain))

FACS

Flow-cytometry using anti-CD4 antibody MT310 Cynomolgus monkey lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of MT310 ( panel B) at a concentration of 1 µg/ml for 30 mins at RT. (Recombinant CD4 抗体 (Extracellular Domain))

FACS

3 images

产品编号 ABIN5668250

发货至: 中国

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中国
北京 101111

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Room 801-803

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Quick Overview for Recombinant CD4 抗体 (Extracellular Domain) (ABIN5668250)

抗原

See all CD4 抗体

CD4

抗体类型

Recombinant Antibody

适用

人, 猕猴, Cynomolgus

宿主

兔

克隆类型

Chimeric

标记

This CD4 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Peptide (BP), Inhibition (Inh)

克隆位点

MT310

Discover our top product CD4 Primary Antibody

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Extracellular Domain

原理

Anti-CD4 [MT310], Rabbit IgG, kappa

特异性

This antibody is specific for the CD4 extracellular domain D1 (binding the HIV-1 gp120-binding site).
Application Notes original Clone: This antibody strongly inhibits HIV-1 gp120-binding to CD4, which blocks HIV infectivity of CD4⁺ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation (possibly leading to anergy induction) (Qin et al., 2001, PMID: n/a). Additionally, antibody binding to CD4 leads to GM-CSF, TNF-α and IL-10 induction. (TNF-α induction only occurs after 20hours.)

交叉反应

Cynomolgus, 猕猴

产品特性

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

纯化方法

Protein A affinity purified

亚型

IgG, kappa
anti-CD4 (CD4) (AA 385-457) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, Pig FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 犬, Pig, 兔, Cow, 绵羊, 豚鼠, 山羊, 马, Avian, 驴, Hamster WB, IHC (fro), IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 适用: 人 FACS, WB, MS 宿主: 小鼠 Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal unconjugated

anti-CD4 (CD4) (AA 301-400) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) (AA 26-200) antibody
CD4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody (PE)
CD4 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-35 PE

anti-CD4 (CD4) antibody
CD4 适用: 小鼠 FACS, IP, ICC, IHC (fro), Func 宿主: 大鼠 Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 FITC

应用备注

Optimal working dilution should be determined by the investigator.

说明

OriginalSpeciesName: Mouse
OriginalFormat: IgG1

限制

仅限研究用
浓度

1 mg/mL

缓冲液

PBS with 0.02 % Proclin 300.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
抗原

CD4

别名

CD4

背景

Leu3/T3, T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3

UniProt

P01730

途径

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events