Recombinant ErbB2/Her2 (Trastuzumab Biosimilar) 抗体
适用: 人
FACS, ELISA, IHC
宿主: Human
Monoclonal
4D5-8
unconjugated
Recombinant Antibody
(1 reference)-
- 抗原 See all ErbB2/Her2 (Trastuzumab Biosimilar) products
- ErbB2/Her2 (Trastuzumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
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Human
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克隆类型
- 单克隆
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标记
- This ErbB2/Her2 (Trastuzumab Biosimilar) antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- 特异性
- Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30 % of invasive breast cancers and 70 % of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
- 产品特性
-
OriginalSpeciesName: Human
OriginalFormat: IgG1
- 纯化方法
- Purified antibody.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
- 克隆位点
- 4D5-8
- 亚型
- IgG1 kappa
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anti-ErbB2/Her2 (Trastuzumab Biosimilar) antibody
适用: 人 FACS, ELISA, IHC 宿主: 兔 Monoclonal 4D5-8 unconjugated Recombinant Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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: "Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer." in: Journal of translational medicine, Vol. 17, Issue 1, pp. 201, (2020) (PubMed).
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: "Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer." in: Journal of translational medicine, Vol. 17, Issue 1, pp. 201, (2020) (PubMed).
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- 抗原
- ErbB2/Her2 (Trastuzumab Biosimilar)
- Abstract
- ErbB2/Her2 (Trastuzumab Biosimilar) 产品
- 别名
- CD340 antibody, HER-2 antibody, HER-2/neu antibody, HER2 antibody, MLN 19 antibody, NEU antibody, NGL antibody, TKR1 antibody, erb-b2 receptor tyrosine kinase 2 antibody, ERBB2 antibody
- 物质类
- Biosimilar
- 背景
- CD340, Metastatic lymph node gene 19 protein (MLN 19), Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, p185HER2, EGFR
- UniProt
- P04626
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