Recombinant CD55 抗体
Quick Overview for Recombinant CD55 抗体 (ABIN5668198)
抗原
See all CD55 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD55 [LU30], Mouse IgG1, lambda
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特异性
- The antibody binds to CD55 with a Kd of 13 nM.
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产品特性
- Human
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纯化方法
- Protein A affinity purified
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免疫原
- Human CD55.
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亚型
- IgG1 lambda
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应用备注
- The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.
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说明
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This chimeric mouse antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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别名
- CD55
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背景
- DAF, Complement decay-accelerating factor
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UniProt
- P08174
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
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