Recombinant CD11b 抗体
Quick Overview for Recombinant CD11b 抗体 (ABIN5668175)
抗原
See all CD11b (ITGAM) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Integrin α-M [107], Mouse IgG1, kappa
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特异性
- This antibody binds to the MIDAS face of the A domain from integrin CD11b.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- Wild type (WT) recombinant CD11b.
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亚型
- IgG1 kappa
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应用备注
- The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 Molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- Integrin alpha-M
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背景
- CD11b, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, Neutrophil adherence receptor, complement receptor 3
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UniProt
- P11215
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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