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Recombinant CD11b 抗体

This anti-CD11b antibody is a 小鼠 单克隆 antibody detecting CD11b in FACS 和 ELISA. Suitable for 人.
产品编号 ABIN5668175
发货至: 中国

Quick Overview for Recombinant CD11b 抗体 (ABIN5668175)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA

克隆位点

107
  • 原理

    Anti-Integrin α-M [107], Mouse IgG1, kappa

    特异性

    This antibody binds to the MIDAS face of the A domain from integrin CD11b.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    Wild type (WT) recombinant CD11b.

    亚型

    IgG1 kappa
  • 应用备注

    The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 Molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    Integrin alpha-M

    背景

    CD11b, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, Neutrophil adherence receptor, complement receptor 3

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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