Recombinant VEGF 抗体
Quick Overview for Recombinant VEGF 抗体 (ABIN5668149)
抗原
See all VEGF 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-VEGF [A.4.6.1], Mouse IgG1, kappa
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特异性
- Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone.
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交叉反应
- 大鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- Recombinant human VEGF.
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亚型
- IgG1 kappa
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应用备注
- This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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别名
- VEGF
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背景
- VEGF-A, Vascular Endothelial Growth Factor, VEGFA, Vascular Permeability Factor, VPF
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UniProt
- P15692
抗原
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