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IL2 Receptor beta 抗体

This anti-IL2 Receptor beta antibody is a 小鼠 单克隆 antibody detecting IL2 Receptor beta in FACS, IP 和 Func. Suitable for 人.
产品编号 ABIN5665749
发货至: 中国

Quick Overview for IL2 Receptor beta 抗体 (ABIN5665749)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

TU27
  • 原理

    Anti-Hu CD122 Purified Low Endotoxin

    特异性

    The mouse monoclonal antibody TU27 recognizes an extracellular epitope of CD122 (IL-2R beta), a 70-75 kDa type I transmembrane glycoprotein constitutively expressed by NK cells and a T cell subset, and upregulated upon activation.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    内毒素水平

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    免疫原

    TL-Mor cell line

    亚型

    IgG1 kappa
  • 应用备注

    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122

    背景

    Interleukin 2 receptor subunit beta,CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.,IL2RB, IL15RB, P70-75

    基因ID

    3560

    UniProt

    P14784

    途径

    JAK/STAT Signaling, Growth Factor Binding
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