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SAV1 抗体 (AA 300-383)

Name: SAV1 抗体 (AA 300-383)
SKU: ABIN566210
Availability: OutOfStock

This anti-SAV1 antibody is a 小鼠单克隆 antibody detecting SAV1 in WB, ELISA, IF 和 IP. Suitable for 人. This Primary Antibody has been cited in 6+ publications.

SAV1 monoclonal antibody (M02), clone 3B2. (SAV1 抗体 (AA 300-383))

Immunofluorescence of monoclonal antibody to SAV1 on HeLa cell. (SAV1 抗体 (AA 300-383))

Detection limit for recombinant GST tagged SAV1 is approximately 0. (SAV1 抗体 (AA 300-383))

ELISA

Immunoprecipitation of SAV1 transfected lysate using anti-SAV1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with SAV1 MaxPab rabbit polyclonal antibody. (SAV1 抗体 (AA 300-383))

Western Blot detection against Immunogen (34. (SAV1 抗体 (AA 300-383))

SAV1 monoclonal antibody (M02), clone 3B2 Western Blot analysis of SAV1 expression in Hela S3 NE . (SAV1 抗体 (AA 300-383))

6 images

(6 references)

产品编号 ABIN566210

发货至: 中国

Datasheet as PDF

Quick Overview for SAV1 抗体 (AA 300-383) (ABIN566210)

抗原

See all SAV1 抗体

SAV1 (Salvador Homolog 1 (SAV1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This SAV1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

3B2

抗原表位
8

4

4

3

1

1

1

1

1

1

1

1
AA 300-383

原理

Mouse monoclonal antibody raised against a partial recombinant SAV1.

序列

HTAEIPDWLQ VYARAPVKYD HILKWELFQL ADLDTYQGML KLLFMKELEQ IVKMYEAYRQ ALLTELENRK QRQQWYAQQH GKNF

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

SAV1 (NP_068590, 300 a.a. ~ 383 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Salvador Homolog 1 (SAV1) (AA 1-210) antibody
SAV1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 1-210) antibody
SAV1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) antibody
SAV1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) antibody
SAV1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 1-383) antibody
SAV1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 300-383) antibody
SAV1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 65-92) antibody
SAV1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 266-315) antibody
SAV1 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) (AA 1-383) antibody
SAV1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Salvador Homolog 1 (SAV1) antibody
SAV1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kai, Tsukamoto, Hijiya, Tokunaga, Nakada, Uchida, Daa, Iha, Takahashi, Nomura, Sato, Mimata, Ikawa, Seto, Matsuura, Moriyama: "Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway." in: The Journal of pathology, Vol. 239, Issue 1, pp. 97-108, (2016) (PubMed).

Schütte, Bisht, Heukamp, Kebschull, Florin, Haarmann, Hoffmann, Bendas, Buettner, Brossart, Feldmann: "Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma." in: Translational oncology, Vol. 7, Issue 2, pp. 309-21, (2014) (PubMed).

Park, Kim, Won, Jeon, Oh, Lee, Kim, Lee: "Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPAR?." in: PLoS ONE, Vol. 7, Issue 1, pp. e30983, (2012) (PubMed).

Li, Luo, Li, Wang, Xiao, Tao, Gong, Hu: "Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system." in: Molecular biology reports, Vol. 39, Issue 8, pp. 8225-30, (2012) (PubMed).

Murakami, Mizuno, Taniguchi, Fujii, Ishiguro, Fukui, Akatsuka, Horio, Hida, Kondo, Toyokuni, Osada, Sekido: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).

Mardin, Lange, Baxter, Hardy, Scholz, Fry, Schiebel: "Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction." in: Nature cell biology, Vol. 12, Issue 12, pp. 1166-76, (2010) (PubMed).
抗原

SAV1 (Salvador Homolog 1 (SAV1))

别名

SAV1

背景

Full Gene Name: salvador homolog 1 (Drosophila)
Synonyms: SAV,WW45,WWP4

基因ID

60485

NCBI登录号

NM_021818

途径

Stem Cell Maintenance