SMURF1 抗体 (AA 165-268)
Quick Overview for SMURF1 抗体 (AA 165-268) (ABIN566098)
抗原
See all SMURF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 165-268
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原理
- Mouse monoclonal antibody raised against a partial recombinant SMURF1.
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序列
- DSGPGRPLSC FMEEPAPYTD STGAAAGGGN CRFVESPSQD QRLQAQRLRN PDVRGSLQTP QNRPHGHQSP ELPEGYEQRT TVQGQVYFLH TQTGVSTWHD PRIP
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交叉反应
- 人, 小鼠
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产品特性
- Antibody Reactive Against Recombinant Protein.
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免疫原
- SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- In 1x PBS, pH 7.4
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).
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: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
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- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
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别名
- SMURF1
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背景
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Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: KIAA1625 -
基因ID
- 57154
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NCBI登录号
- NM_020429
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途径
- Regulation of Cell Size
抗原
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