PMEPA1 抗体 (AA 181-280)
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北京 101111
Quick Overview for PMEPA1 抗体 (AA 181-280) (ABIN566055)
抗原
See all PMEPA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 181-280
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原理
- Mouse monoclonal antibody raised against a partial recombinant TMEPAI.
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序列
- NRTIFDSDLM DSARLGGPCP PSSNSGISAT CYGSGGRMEG PPPTYSEVIG HYPGSSFQHQ QSSGPPSLLE GTRLHHTHIA PLESAAIWSK EKDKQKGHPL
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交叉反应
- 人
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产品特性
- Antibody Reactive Against Recombinant Protein.
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免疫原
- TMEPAI (AAH15918, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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亚型
- IgG2a
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anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibody
PMEPA1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PMEPA1-2696 unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 173-252) antibodyPMEPA1 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PMEPA1-2697 unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 21-120) antibodyPMEPA1 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 101-150) antibodyPMEPA1 适用: 人 IHC, WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- In 1x PBS, pH 7.4
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).
: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." in: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).
: "Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma." in: Cancer research, Vol. 73, Issue 13, pp. 3888-901, (2013) (PubMed).
: "TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways." in: Carcinogenesis, Vol. 34, Issue 8, pp. 1764-72, (2013) (PubMed).
: "High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone." in: Cellular & molecular biology letters, Vol. 12, Issue 3, pp. 370-7, (2012) (PubMed).
: "TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling." in: Molecular cell, Vol. 37, Issue 1, pp. 123-34, (2010) (PubMed).
: "Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer." in: Cancer research, Vol. 70, Issue 15, pp. 6377-83, (2010) (PubMed).
: "A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28988-95, (2008) (PubMed).
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: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).
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- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
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别名
- PMEPA1
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背景
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Full Gene Name: prostate transmembrane protein, androgen induced 1
Synonyms: STAG1,TMEPAI -
基因ID
- 56937
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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