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PMEPA1 抗体 (AA 181-280)

This anti-PMEPA1 antibody is a 小鼠 单克隆 antibody detecting PMEPA1 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN566055
发货至: 中国

Quick Overview for PMEPA1 抗体 (AA 181-280) (ABIN566055)

抗原

See all PMEPA1 抗体
PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

适用

  • 48
  • 2
  • 1

宿主

  • 36
  • 12
小鼠

克隆类型

  • 37
  • 11
单克隆

标记

  • 22
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
This PMEPA1 antibody is un-conjugated

应用范围

  • 38
  • 30
  • 12
  • 10
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

2A12
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-280

    原理

    Mouse monoclonal antibody raised against a partial recombinant TMEPAI.

    序列

    NRTIFDSDLM DSARLGGPCP PSSNSGISAT CYGSGGRMEG PPPTYSEVIG HYPGSSFQHQ QSSGPPSLLE GTRLHHTHIA PLESAAIWSK EKDKQKGHPL

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    TMEPAI (AAH15918, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ó hAinmhire, Quartuccio, Cheng, Ahmed, King, Burdette: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).

    Singha, Pandeswara, Geng, Lan, Venkatachalam, Saikumar: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." in: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).

    Costea, Hills, Osman, Thurlow, Kalna, Huang, Pena Murillo, Parajuli, Suliman, Kulasekara, Johannessen, Partridge: "Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma." in: Cancer research, Vol. 73, Issue 13, pp. 3888-901, (2013) (PubMed).

    Hu, He, Wang, Yuan, Liu, Ji, Song: "TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways." in: Carcinogenesis, Vol. 34, Issue 8, pp. 1764-72, (2013) (PubMed).

    Hirokawa, Takagi, Uchida, Kozuka, Yoneda, Watanabe, Shiraishi: "High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone." in: Cellular & molecular biology letters, Vol. 12, Issue 3, pp. 370-7, (2012) (PubMed).

    Watanabe, Itoh, Goto, Ohnishi, Inamitsu, Itoh, Satoh, Wiercinska, Yang, Shi, Tanaka, Nakano, Mommaas, Shibuya, Ten Dijke, Kato: "TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling." in: Molecular cell, Vol. 37, Issue 1, pp. 123-34, (2010) (PubMed).

    Singha, Yeh, Venkatachalam, Saikumar: "Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer." in: Cancer research, Vol. 70, Issue 15, pp. 6377-83, (2010) (PubMed).

    Li, Xu, Masuda, Raymundo, McLeod, Dobi, Srivastava: "A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28988-95, (2008) (PubMed).

  • 抗原

    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

    别名

    PMEPA1

    背景

    Full Gene Name: prostate transmembrane protein, androgen induced 1
    Synonyms: STAG1,TMEPAI

    基因ID

    56937

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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