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RAD18 抗体 (AA 332-430)

Cited in 7+ publications. This anti-RAD18 antibody is a 小鼠 单克隆 antibody detecting RAD18 in WB, ELISA, IF, IHC (p) 和 RNAi. Suitable for 人.
产品编号 ABIN566046
发货至: 中国
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中国
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Quick Overview for RAD18 抗体 (AA 332-430) (ABIN566046)

抗原

See all RAD18 抗体
RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RAD18 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

3H7
  • 抗原表位

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    AA 332-430

    原理

    Mouse monoclonal antibody raised against a partial recombinant RAD18.

    序列

    EKEIDEIHSK YRKKHKSEFQ LLVDQARKGY KKIAGMSQKT VTITKEDEST EKLSSVCMGQ EDNMTSVTNH FSQSKLDSPE ELEPDREEDS SSCIDIQEV

    交叉反应

    人, 大鼠

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    RAD18 (NP_064550, 332 a.a. ~ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Sy, Jiang, O, Deng, Huen: "The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks." in: Nucleic acids research, Vol. 41, Issue 18, pp. 8572-80, (2013) (PubMed).

    Wong, Aguissa-Touré, Wani, Khosravi, Martinka, Martinka, Li: "Elevated expression of Rad18 regulates melanoma cell proliferation." in: Pigment cell & melanoma research, Vol. 25, Issue 2, pp. 213-8, (2012) (PubMed).

    Kato, Waki, Umezawa, Aoki, Utsugi, Ohtsu, Murakami: "Phosphorylation of human INO80 is involved in DNA damage tolerance." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 433-8, (2012) (PubMed).

    Wong, Lin, Khosravi, Piche, Jafarnejad, Chen, Li: "Tumour suppressor ING1b maintains genomic stability upon replication stress." in: Nucleic acids research, Vol. 39, Issue 9, pp. 3632-42, (2011) (PubMed).

    Yanagihara, Kobayashi, Tateishi, Kato, Matsuura, Tauchi, Yamada, Takezawa, Sugasawa, Masutani, Hanaoka, Weemaes, Mori, Zou, Komatsu: "NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol ?-dependent translesion DNA synthesis." in: Molecular cell, Vol. 43, Issue 5, pp. 788-97, (2011) (PubMed).

    Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." in: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).

    Kobayashi, Okui, Asaithamby, Burma, Chen, Tanimoto, Matsuura, Komatsu, Chen: "WRN participates in translesion synthesis pathway through interaction with NBS1." in: Mechanisms of ageing and development, Vol. 131, Issue 6, pp. 436-44, (2010) (PubMed).

  • 抗原

    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

    别名

    RAD18

    背景

    Full Gene Name: RAD18 homolog (S. cerevisiae)
    Synonyms: RNF73

    基因ID

    56852

    NCBI登录号

    NM_020165
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